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Industry News

What is Mushroom Beta Glucan?

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Author : Samantha Song
Update time : 2025-09-24 11:01:44
Mushroom Beta Glucan is a polysaccharide compound derived from the fruit-body and mycelia (roots) of the mushrooms. Numerous studies have shown that this substance effectively enhances the immune system by activating the white blood cells including the macrophages, T cells, and the natural killer (NK) cells. (Lindequist et al., The Phamacological Potential of Mushrooms, 2005). The Macrophages (Monocytes), Granulocytes (Neutrophil, Eosinophils, and the Basophils), and the Natural Killer (NK) cells serve as the frontline of defense. These cells in the immune system are responsible finding, identifying, and consuming foreign invaders and further activate other components of the immune system to produce of other immune cells, including B-cells, T-cells and Natural Killer (NK) cells in preparation of the future adverse events.

Common Sources (Mushroom Types):
Different mushrooms contain varying types and potencies of beta-glucans. Some of the most popular and well-researched sources include:
Reishi: Known as the "Mushroom of Immortality," highly valued for immune and adaptogenic (stress-reducing) support.
Shiitake: Contains lentinan, a well-studied beta-glucan.
Maitake: Rich in beta-glucans known for their health benefits.
Turkey Tail: Famous for its high concentration of polysaccharopeptides (PSP and PSK), which are beta-glucan-protein complexes.


Why is Our Beta Glucan from Mushrooms More Potent and Effective?

1. Our mushroom beta glucan provides more “branches,” or binding sites yielding a more effective than the beta 1,3-Glucan configuration, higher than the industry standard and most others commercially available.
 

2. Products from grains (oats and barley) were demonstrated to lower cholesterol and upgrading frontline immunity. However, in addition to the above efficacy, the mushroom-derived beta glucan modulates the activities of all immune cells including macrophages, NK cells and neutrophils, resulting in a better immune modulation. Except beta Glucan, mushrooms also contain heat-stable lectin which directs activation of T-cells. In comparison, mushroom immno-modulatory substances are more versatile and outperform those from yeast and grains.
 

3. Our Mushroom Beta Glucan is highly purified: The cell walls of the mushrooms are a glucose shell coated with an outer layer of manno-proteins. If the beta glucan is not sufficiently purified, with the manno-protein, plasma membrane and fibrillar layer (the outermost layer of the fungal cell wall) intact and not removed, then the inner beta glucan layer is not exposed. In other words, it will not be recognized by the beta glucan receptors on the macrophage. Most beta glucans on the market are simply baker’s yeast, and / or crude, impure beta-glucan and will not have the full macrophage activating capability.
 

4. Micronization of Beta glucan molecules: We have micronized the surface area so that more configuration surface will be available for activating macrophage. The configuration, correct chain length molecule, highly purified form and the micronization of Mushroom Beta-glucan is what makes our Mushroom beta-Glucan to be unique and different.
 

5. Our Germ-Free Cultivating methods are more efficient producing the specific substances needed. This includes proper fertilizing, temperature, climate and air control, light and fermentation technology. All this, combined with proper separation and purification of various high-molecular weight mushroom Beta-Glucan, as well as our fractionation, concentration and freeze-drying methods, has produced top-notch commercial quality and efficacy.

What is The Difference Between Hefei Dielegance Biotechnology Co., Ltd.'s Mushroom Extracts and Other Products Made with Pulverized Powders from Raw Mushrooms?
First of all, the nutritional value of healthcare mushrooms in its raw form contains mostly fibers without any further processing. It is difficult for the digestive system to absorb the active ingredients of raw mushrooms without any extraction. Traditionally, dried healthcare mushrooms were boiled in hot water and consumed in a tea/soup in order to properly digest the active ingredients. This is commonly known as the hot-water extraction procedure. Even the ancestors understood the importance of consuming the extracts rather than the raw mushroom powders. Therefore, mushroom products in the market place are made only with the pulverized powder from raw mushrooms are simply NOT EFFECTIVE and could potentially induce hypersensitivity in your pets due to the higher purine and other allergen levels.


If you would like to purchase or buy highly-effective Mushroom Beta Glucan powder, please kindly get back to our company website: https://www.dxextract.com/collections/fungus-extract/1.html;
or contact us via s.samantha@dielegancebiotech.com.
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