Product Description

Niacinamide (CAS 98-92-0), also known as nicotinamide, is the water-soluble amide form of vitamin B3. It appears as a white crystalline powder, odorless or with a slight bitter taste, freely soluble in water and ethanol, and soluble in glycerin. As one of the most extensively researched and widely used active ingredients in cosmetic formulations, niacinamide supports skin health through multiple pathways.

Our niacinamide powder meets In-house standards with ≥99% purity, suitable for serums, creams, lotions, cleansers, and mask formulations.

Quick Details

Key Benefits & Scientific Support

1) Barrier Repair & Moisture Support — Niacinamide stimulates de novo synthesis of ceramides and other stratum corneum lipids, enhancing the epidermal permeability barrier. One study demonstrated that niacinamide treatment of cultured human keratinocytes increased ceramide synthesis rates 4.1–5.5 fold in a dose-dependent manner, with corresponding increases in serine palmitoyltransferase (SPT) activity. Topical niacinamide increases stratum corneum ceramide and free fatty acid levels while reducing transepidermal water loss (TEWL).

2) Sebum Control & Pore Management — A clinical study demonstrated that 2% niacinamide effectively regulates facial sebum secretion, supporting daily care for oily and combination skin.

3) Anti-Aging & Skin Tone Improvement — Multiple clinical studies confirm that topical niacinamide improves various visual parameters of aging facial skin, including reduction of sallowness (yellowing), fine lines, redness, and hyperpigmented spots. Niacinamide has been shown to have multi-modal mechanisms of action in skin care, partially preventing or reversing biological changes associated with skin aging.

4) Acne Support — A 2024 randomized controlled trial showed that a moisturizer containing ceramides and niacinamide, when used in combination with anti-acne medication, significantly improved non-inflammatory, inflammatory, and total lesion counts in mild-to-moderate acne, while also improving skin hydration and sebum secretion.

Recommended Usage

Why Choose Our Niacinamide Powder?

• ≥99% HPLC purity — reliable batch-to-batch consistency

• USP standard — meets international pharmacopoeial quality requirements

• Freely water-soluble — simple formulation processing

• Multi-pathway benefits — barrier, sebum control, anti-aging, skin tone

• Full documentation — CoA, MSDS, TDS available

Request some sample or want to order the Niacinamide/Nicotinamide Powder, Contact DIELEGANCE BIOTECH technical sales team to ask more details for supporting your formulations.