Product Description

5-Deazaflavin (CAS 26908-38-3), also known as Pyrimido[4,5-b]quinoline-2,4(1H,3H)-dione, is a synthetic flavin derivative structurally derived from riboflavin (vitamin B2) through a unique modification: the nitrogen atom at position 5 of the flavin nucleus is replaced by a carbon atom. This subtle structural change fundamentally alters the molecule‘s redox behavior, transforming it from a classic flavin into a “flavin-shaped nicotinamide derivative” with distinct electrochemical properties.

Our 5-Deazaflavin powder is a synthetic, high-purity compound (≥98% HPLC) appearing as a light yellow to light gray crystalline powder. Unlike naturally derived flavins, 5-deazaflavin lacks the single-electron reactivity with oxygen that characterizes riboflavin-derived coenzymes, giving it a more negative redox potential and unique stability profile.

Quick Details

The Main Applications for High Purity 5-Deazaflavin Powder?

1) Cosmetics & Personal Care
5-Deazaflavin is positioned as a next-generation anti-aging active for skincare formulations. In the Japanese beauty market, it has been described as an ingredient that addresses “cellular aging” and “mitochondrial dysfunction”—the root causes of visible aging signs.

Key Benefits for Skincare:
Antioxidant protection against environmental stress
Supports skin metabolism and turnover
Helps improve skin firmness, softness, and brightness
Addresses visible signs of aging including fine lines and loss of elasticity 

Recommended Use Level: 0.01–0.1% (formulation-dependent)

Common Formats: Serums, creams, ampoules, mask powders

2) Nutraceuticals & Dietary Supplements
5-Deazaflavin is used in dietary supplement formulations targeting cellular energy and healthy aging. In Japan, it is supplied exclusively for OEM products with a recommended daily intake of 30–60 mg/day.

Common Formats: Capsules, tablets, powder blends

Synergistic Ingredients: NMN, NAD+, Ergothioneine 

3) Research & Pharmaceutical Development
5-Deazaflavin serves as a research reference standard and is explored in pharmaceutical development.

Why Choose Our 5-Deazaflavin Powder?

≥98% HPLC-verified purity — consistent batch-to-batch quality 

Synthetic origin — controlled production for reliable supply

Documented research support — peer-reviewed studies on redox chemistry, ATP production, and antioxidant stress protection

Full documentation — CoA, MSDS, TDS available upon request 

Flexible packaging — quantities from R&D to commercial scale

Request some sample or want to order the 5-Deazaflavin Powder, Contact DIELEGANCE BIOTECH technical sales team to ask more details for supporting your formulations.