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Quercetin 95% CAS 117-39-5: High-Purity Flavonoid for Premium Nutraceutical & Skincare Formulations

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Author : Samantha Song
Update time : 2026-09-03 10:51:50

Product Description

Quercetin (CAS 117-39-5) is a naturally occurring flavonoid belonging to the polyphenolic phytochemicals group, widely distributed in fruits, vegetables, and medicinal plants. Chemically known as 3,3',4',5,7-pentahydroxyflavone, quercetin is one of the most extensively studied flavonoids for its biological activities and potential health applications.

Our quercetin is available in a 95% purity grade (HPLC-verified), sourced from natural plant materials and processed through controlled extraction to ensure consistent quality, batch-to-batch reliability, and full regulatory documentation support.


Key Product Specifications

Product Name

Quercetin

CAS Number

117-39-5

Molecular Formula

C₁₅H₁₀O₇

Molecular Weight

302.24 g/mol

Purity (HPLC)

≥95.0%

Appearance

Yellow to yellow-brown crystalline powder

Melting Point

314–317°C

Solubility

Practically insoluble in water; soluble in DMSO (68 mg/mL), ethanol (21 mg/mL), acetic acid (1 mg/mL), aqueous alkali (1 mg/mL)

Loss on Drying

≤5.0%

Heavy Metals

Pb ≤3 ppm; As ≤1 ppm; Cd ≤1 ppm; Hg ≤0.1 ppm

Microbiological

TPC ≤1,000 CFU/g; Yeast & Mold ≤100 CFU/g; E. coli and Salmonella negative

Storage

Cool, dry, light-protected; sealed container away from oxidizing agents

 

 

Mechanism of Action for High Purity Quercetin Powder

Quercetin functions through multiple pathways with potential relevance to various physiological systems:

Antioxidant Support — Neutralizes free radicals and chelates transition-metal ions, supporting the body's natural defense mechanisms against oxidative stress

Inflammatory Response Modulation — Modulates inflammatory signaling pathways, including NF-κB inhibition, supporting healthy inflammatory balance

Enzyme Inhibition — Acts as a stimulator of SIRT1 and inhibitor of PI3K with documented activity

Nrf2 Pathway Activation — Upregulates nuclear Nrf2 protein and downstream antioxidant enzymes (SOD, HO-1, GCLC), supporting cellular antioxidant defense


The Main Applications for Quercetin 95% CAS 117-39-5 Powder

Nutraceuticals & Dietary Supplements

Quercetin is a widely used ingredient in premium supplement formulations, typically positioned for antioxidant support, immune health, and healthy aging.

Common Formats:

  • Capsules and tablets

  • Powder blends for functional beverages

  • Combination formulations with other flavonoids or bioflavonoid complexes

Typical Dosage Reference: 50–250 mg per serving depending on formulation and target application.


Functional Foods and Beverages

Quercetin can be incorporated into fortified beverages, health bars, and other functional food products due to its documented antioxidant and anti-inflammatory properties.


Cosmetics & Personal Care

Quercetin's antioxidant and skin-protective properties make it a valuable ingredient in premium skincare formulations targeting environmental protection and healthy aging.

Common Formats:

  • Anti-aging serums and creams

  • Antioxidant protective treatments

  • Sun protection formulations (as a supporting active)
     

Research & Reference Standards

The 95% grade can serve as a research-grade material for analytical reference and biological studies.
 

Formulation Considerations

For Capsules and Tablets:

  • Blend directly with appropriate excipients (microcrystalline cellulose, etc.)

  • Ensure uniform mixing for consistent dosing

  • Dissolution enhancement: lactose monohydrate (at 10% concentration) has been shown to improve quercetin tablet dissolution time, suggesting stable tablet formulations can be developed with appropriate excipient selection

For Liquid Formulations:

  • Pre-dissolve in ethanol or DMSO before incorporating into aqueous systems

  • Alternative approaches: use of biocompatible solvents such as choline-tryptophan ionic liquids has been shown to enhance quercetin solubility in aqueous systems

  • Protect from light using amber packaging

 

For Cosmetic Formulations:

  • Incorporate into the oil phase or use appropriate solubilizers

  • Consider advanced delivery systems (liposomes, nanoparticles) to enhance bioavailability


Why Choose Our Quercetin 95%?

✅ HPLC-verified ≥95% purity — consistent batch-to-batch quality

✅ Full batch traceability — from plant source to finished powder

✅ Comprehensive documentation — CoA, MSDS, TDS available

✅ Technical formulation support — assistance with stability and application

✅ Flexible supply options — quantities to meet your production needs


Request some sample or want to order the high purity quercetin powder, Contact DIELEGANCE BIOTECH technical sales team to ask more details for supporting your formulations.


Related Products:

Dihydroquercetin Powder
Rutin Powder
Vitamin C Powder

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